Benue State University, Makurdi

MEDICATION ADHERENCE MODERATES THE INFLUENCE OF DEPRESSION ON QUALITY OF LIFE AMONG PEOPLE LIVING WITH SCHIZOPHRENIA

Oladejo Teslim Alabi, Ajele Kenni Wojujutari, Saka Saheed Abiola, and Lawal Musbau Abiodun

Abstract

The study examined the moderating effect of medication adherence on the influence of depression on quality of life and investigated the gender differences on quality of life among people living with schizophrenia. The study conducted a cross-sectional survey design. A convenience sample of 188 (59.1% Males & 40.9% Females) people living with schizophrenia who were receiving follow-up clinical treatment in psychiatry department, Federal Medical Centre, Lokoja were used. Data were collected using the Morisky Medication Adherence Scale (MMAS–8), Calgary Depression Scale (CDSS), stigma scale of Epilepsy (SSE) and World Health Organization Quality of Life-BREF Scale (WHOQOL-BREF). The data were analysed using Moderation and Conditional Process Analysis. The analyses were carried out with ROCESS Macro for IBM/SPSS Version 22.0. The Results showed positive significant influence of depression on quality of life of people living with schizophrenia. The results further revealed positive significant influence of medication adherence on quality of life people living with schizophrenia and also, the findings further revealed significant negative moderating effects of medication adherence on quality of life of people living with schizophrenia. Lastly, results further showed type of gender has significant difference on patient's quality of life.This study concluded that quality of life of people living with schizophrenia that is influenced by depression is moderated by their medication adherence.

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