Human Resource Management (HRM) is pivotal in shaping employee performance and organisational success, particularly in competitive and dynamic business environments. This study examines the impact of HRM on employee performance in Nigerian Breweries Plc, Makurdi plant, focusing on organisational culture, HRM practices, talent management strategies, and barriers to effective HRM. A survey research design was adopted, with a total population of 135 staff, from which a sample of 100 respondents was proportionally drawn across departments. Data were collected using structured questionnaire and analysed using descriptive and inferential statistics. Findings reveal that a supportive organisational culture positively influences HRM practices, enhancing employee motivation, engagement, and overall performance. HRM practices, including training, performance appraisal, and communication, significantly improve job satisfaction and employee commitment. Talent management strategies such as recruitment, training, succession planning, and performance-based incentives effectively attract, retain, and develop skilled employees, although structural limitations and resource constraints hinder optimal outcomes. Barriers such as bureaucratic delays, inconsistent appraisals, limited training, and communication gaps negatively affect HRM effectiveness and employee performance. The study concludes that strategic and well-implemented HRM practices are essential for maximising employee productivity and sustaining organisational competitiveness. Recommendations include fostering a supportive culture, continuous training, effective talent management, and streamlining HR processes to enhance performance.