This “study titled; Impact of Exchange Rate Fluctuations on Performance of the Manufacturing Sector in Nigeria (1993–2024), investigated how variations in exchange rate influenced the growth of Nigeria’s manufacturing sector between 1993 and 2024. Growth rate of the manufacturing sector served as the dependent variable, while exchange rate was the explanatory variable, whereas, inflation rate, and public capital expenditure on infrastructure served as control variables. Secondary data used were sourced from the Central Bank of Nigeria, Statistical Bulletin. The study adopted the Autoregressive Distributed Lag (ARDL) technique for the analysis of data. The empirical findings suggested that exchange rate has positive and statistically insignificant relationship with manufacturing sector growth in Nigeria. In contrast, inflation rate showed a negative and statistically significant effect on manufacturing growth during the period examined. Similarly, public capital expenditure on infrastructure demonstrated a negative and statistically significant relationship with the growth rate of the manufacturing sector. The study concludes that stable exchange rate, improved and adequate infrastructure and stable inflation rate will enhance manufacturing sector growth in Nigeria It suggested that monetary authorities, particularly the Central Bank, should implement policies aimed at maintaining exchange rate stability. Central Bank of Nigeria (CBN) should also pursue policies to reduce inflation rate to a stable single-digit, within the Nigerian economy. Furthermore, the government should prioritize infrastructure development tailored to the needs of the manufacturing sector in order to enhance” its performance.